Tag Archives: curcumin

2 More Studies on Turmeric Curcumin

The ancient Indian spice turmeric strikes again!

Learn why Turmeric is effective in neutralizing SAR-CoV-2, for many of the same reasons it is also effective for renegade cell growth, aka cancer.

1. Turmeric Root and Its Bioactive Ingredient Curcumin Effectively Neutralize SARS-CoV-2 In Vitro

The application of turmeric root in herbal medicine has a very long history.

Its bioactive ingredient curcumin shows a broad-spectrum antimicrobial activity. In the present study, we investigated the antiviral activity of aqueous turmeric root extract, the dissolved content of a curcumin-containing nutritional supplement capsule, and pure curcumin against SARS-CoV-2.

Turmeric root extract, dissolved turmeric capsule content, and pure curcumin effectively neutralized SARS-CoV-2 at subtoxic concentrations in Vero E6 and human Calu-3 cells. Furthermore, curcumin treatment significantly reduced SARS-CoV-2 RNA levels in cell culture supernatants. Our data uncovers curcumin as a promising compound for complementary COVID-19 treatment. Curcumin concentrations contained in turmeric root or capsules used as nutritional supplements completely neutralized SARS-CoV-2 in vitro.

https://www.mdpi.com/1999-4915/13/10/1914

 

 

 

 

 

 

 

 

 

2. This study finds turmeric extract selectively and safely killing cancer stem cells in a way that chemo and radiation can not.

A groundbreaking new study published in the journal Anticancer Research reveals that one of the world’s most extensively researched and promising natural compounds for cancer treatment: the primary polyphenol in the ancient spice turmeric known as curcumin, has the ability to selectively target cancer stem cells, which are at the root of cancer malignancy, while having little to no toxicity on normal stem cells, which are essential for tissue regeneration and longevity.

Titled, “Curcumin and Cancer Stem CellsCurcumin Has Asymmetrical Effects on Cancer and Normal Stem Cells,” the study describes the wide range of molecular mechanisms presently identified by which curcumin attacks cancer stem cells (CSCs), which are the minority subpopulation of self-renewing cells within a tumor colony. These cells  are capable of producing all the other cells within a tumor, making them the most lethal, tumoriogenic of all cells within most, if not all, cancers.

Because CSCs are resistant to chemotherapy, radiation, and may even be provoked towards increased invasiveness with surgery, they are widely believed to be responsible for tumor recurrence and the dismal failure of conventional treatment.

The study identified the following 8 molecular mechanisms by which curcumin targets and kills cancer stem cells:

  • Down-regulation of interleukin-6 (IL-6): IL-6 is classified as a cytokine (a potent biomolecule released by the immune system) and modulates both immunity and inflammation. It’s over expression has been linked to the progression from inflammation to cancer. Curcumin inhibits IL-6 release, which in turn prevents CSC stimulation.
  • Down-regulation of interleukin-8 (IL-8): IL-8, another cytokine, is released after tumor cell death, subsequently stimulating CSCs to regrow the tumor and resist chemotherapy. Curcumin both inhibits IL-8 production directly and indirectly.
  • Down-regulation of interleukin-1 (IL-1): IL-1, a family of cytokines, are involved in response to injury and infection, with IL-1 ? playing a key role in cancer cell growth and the stimulation of CSCs. Curcumin inhibits IL-1 both directly and indirectly.
  • Decrease CXCR1 and CXCR2 binding: CXCR1 and CXCR2 are proteins expressed on cells, including CSCs, which respond to the aforementioned cytokines in a deleterious manner. Curcumin has been found to not only block cytokine release, but their binding to these two cellular targets.
  • Modulation of the Wnt signaling pathway: The Wnt signaling pathway regulates a wide range of processes during embryonic development, but are also dsyregulated in cancer. Curcumin has been found to have a corrective action on Wnt signaling.
  • Modulation of the Notch Pathway: The Notch signaling pathway, also involved in embryogenesis, plays a key role in regulating cell differentiation, proliferation and programmed cell death (apoptosis), as well as the functioning of normal stem cells. Aberrant Notch signaling has been implicated in a wide range of cancers. Curcumin has been found to suppress tumor cells along the Notch pathway.
  • Modulation of the Hedgehog Pathways: Another pathway involved in embryogenesis, the Hedgehog pathway also regulates normal stem cell activity. Abnormal functioning of this pathway is implicated in a wide range of cancers and in the stimulation of CSCs and associated increases in tumor recurrence after conventional treatment. Curcumin has been found to inhibit the Hedgehog pathway through a number of different mechanisms.
  • Modulation of the FAK/AKT/FOXo3A Pathway: This pathway plays a key role in regulating normal stem cells, with aberrant signaling stimulating CSCs, resulting once again in tumor recurrence and resistance to chemotherapy. Curcumin has been found in multiple studies to destroy CSCs through inhibiting this pathway.

As you can see through these eight actions, curcumin exhibits a rather profound level of complexity, modulating numerous molecular pathways simultaneously.

Conventional cytotoxic chemotherapy is incapable of such delicate and “intelligent” behavior, as it preferentially targets fast-replicating cells by damaging their DNA , regardless of whether they are benign, healthy or cancerous cells. This includes fast replicating cells such as the stomach lining which are essential for us to digest food to gain nutrition for healing!  Curcumin’s selective cytotoxicity targets the cancer stem cells.

Curcumin and Normal Stem Cells

Normal stem cells (NSCs) are essential for health because they are responsible for differentiating into normal cells that are needed to replace damaged or sick ones. If curcumin were to kill normal cells, like radiation and chemotherapy, it would not provide a compelling alternative to these treatments.  The study addressed this point:

“The safety of curcumin has been long established, as it has been used for centuries as a dietary spice. The question arises as to why curcumin does not seem to have the same deleterious effects on normal stem cells (NSCs) as it does on CSCs. There are several possible reasons that curcumin has toxic effects on CSCs, while sparing NSCs.”
The study offered three potential explanations for curcumin’s differential or selective cytotoxicity:
  • Malignant cells take in much more curcumin than normal cells. This is similar to properties of Paw Paw Cell Reg  (Asimina triloba), as explained in Benoit’s book, “The Paw Paw Program“.
  • Curcumin alters the microenvironment of cells in such a way that is adverse to CSCs and beneficial to NSCs.
  • Curcumin may not only directly attack CSCs, but may encourage them to differentiate into non-lethal, more benign cells.

Concluding Remarks

This study adds growing support to the idea that safe, time-tested, natural substances are superior to synthetic ones. Given the evidence that a safe and effective alternative may already exist, chemotherapy, radiation and even surgery may no longer be justified as the first-line standard of care for cancer treatment.

In fact, a significant body of evidence now implicates these treatments in worsening prognosis, and in some cases driving cancer stem cell enrichment in tumors.

Radiotherapy, for instance, has been found to induce cancer stem cell-like properties in breast cancer cells, essentially increasing their malignancy and tumoriogenicity by 30 fold.  This is hardly progress when one considers the role that CSCs play, especially in contributing to post-treatment secondary cancers.

Turmeric and its components are not FDA approved drugs, and by definition the FDA will not allow an unapproved substance, natural or synthetic, to prevent, treat, diagnosis or cure a disease.  This means that you will not be seeing it offered by an oncologist as an alternative to chemotherapy or radiation any time soon.  This does not, however, mean that it does not work.

There are  over 1500 citations from the National Library of Medicine’s database MEDLINE on Turmeric Research, showing that curcumin and related turmeric components possess significant anti-cancer activity.
Please contact our office to order quality and potent turmeric, 50:1 extract.  One of Nature’s Sunshine Turmeric Curcumin capsules contains the potency of 10 – 200 capsules of other brands, as tested by independent labs.
NSP has not been leader in herbs since 1972 without good reason!

Turmeric Curcumin with Black Pepper

Nov. 2018 Update: Same product, same quality, name changed from CureQMin BP to Turmeric Curcumin, for ease of identification.

Cindy Klement, Master Nutritionist presented at the Canadian NSP Herbal  Conference. We learned that the new Turmeric Curcumin contains  a concentrated extract from the fruit of black pepper, piper nigrum. This increases  the absorption of the concentrated curcuminoids  from turmeric and therefore the effectiveness  by 2000%. There is no Turmeric on the market that competes with this Nature’s Sunshine brand. The curcuminoid content of 2 capsules equals as much as 200 of some competitor brands, when tested by approved independent labs.

I love Nature’s Sunshine products as they are the most superior herbal products on the market. Turmeric has been studied for powerful properties that have a beneficial effect on pain and inflammation of all types. This article on Herbs Are Effective – 5000 years of science highlights some studies.

Each capsule contains Curcuma longa (curcumin) rhizome 550 mg, Piper nigrum (black pepper) fruit extract (50:1) 2.5 mg.

The 50:1 means it is concentrated 50 times.

Please contact Benoit Health Education to order the best at the best prices, whichever country you live in; we can guide you to optimum health!

Herbs ARE Effective – Science Recognizes 5000+ Years History

Below are 3 quotes from learned people that give us food for thought about keeping an open mind and looking outside the box on many “accepted” ideas:

“This ‘telephone’ has too many shortcomings to be seriously considered as a means of communication. The device is inherently of no value to us.” Western Union internal memo, 1876

“I think there is world market for maybe five computers” -Thomas Watson, chairman of IBM, 1943

640K ought to be enough for anybody.” – Bill Gates, 1981

It is as hard to believe that these statements were taken seriously,  as it that people once believed that the world was flat. Or that rampant cell growth, aka cancer,  can only be treated with surgery, chemical poisons or radiation. This gives you some idea why the title of Lorene Benoit’s book on healing is named:  The Paw Paw Program – A “Christopher Columbus” Approach to Cancer – The World IS Round and Cancer CAN Be Treated Naturally.

Having  been in the natural health field since 1974, and seriously using herbs since 1980, it is very heartening to see science supporting traditional healing more every day. Not that I need the proof, having seen life changing results with natural healing for thousands of people,  but this may help move the public toward a better understanding of why herbal healing is still around after more than 5000 years. And why it is important to look outside the box and learn to take more control of our own health for a healthier, happier life!

New research from Thailand indicates curcumin may be as effective as ibuprofen in relieving osteoarthritis pain.      

In a study involving 367 patients (mean age 60 years) with knee osteoarthritis, subjects were randomized into two groups who received either ibuprofen (1,200 mg/day) or a turmeric extract (75-85% total curcuminoids, 1,500 mg/day) for four weeks. Treatment efficacy was assessed via the Western Ontario and McMaster Universities Osteoarthritis Index for pain, stiffness and  function scores.

Comparison of WOMAC scores showed significant improvement from baseline in both the ibuprofen and curcumin groups, with no significant difference between the two groups. While both treatments were generally well tolerated, there were fewer reports of adverse gastrointestinal side-effects in the curcumin group. These findings are consistent with previous research showing curcumin to be similar or more effective than ibuprofen in efficacy and much safer for all forms of inflammation.

References: Kuptniratsaikul V, Thanakhumtorn S, et al. Efficacy and safety of Curcuma domestica extracts in patients with knee osteoarthritis.
Clin Interv Aging 2014 Mar 20;9:451–8.doi:10.2147/CIA.S58535 
AlternComplement Med. 2009 Aug; 15 (8):891-7. doi: 10.1089/acm.2008.0186

Nature’s Sunshine Turmeric Curcumin Concentrated contains 400 mg of curcuminoids provided by the internationally recognized Curcumin C3 Complex®. This ingredient is patented for its unique composition ratio of the bioactive curcuminoids (95%) extracted from turmeric roots. The Curcumin C3 Complex® is highly regarded in the clinical literature for consistency, quality and integrity of the three main antioxidant and protective compounds found in turmeric root, collectively known as curcuminoids. It has the been the clinical trial material of choice for a significant number of research studies investigating its protective, antioxidant and inflammation – mediating benefits.

 

Stress is far worse for cardiovascular health than cholesterol will ever be

Dr. Stephen Sinatra ( no, not Frank) , MD, FACN tells us clearly shows that emotions have a tremendous effect on our physical health. He lists five of the most common negative emotions: Anger, Sadness, Heartbreak, Stress  and Generalized Anxiety Disorder (GAD). I love that last one – anytime enough people have similar challenges, an new “disorder” is created, usually to promote a new drug to treat the new disorder.

What these 5 stressful emotions have in common is that they all produce hormones such as cortisol, adrenaline and nor-adrenaline. Among other effects, these hormones  thicken the blood, and create inflammation. So instead of ingesting rat poison, aka blood thinners, consider reducing these negative emotions and supplementing your diet with  a good quality Nutri -Calm (US)/ Stress Formulas (CA)), which contain both herbs and B Vitamins. Besides helping reduce the physical effects of stress, this formula  also helps lower homocysteine levels related to Cardiovascular health.

Stress related emotions also decrease essential mineral such as Potassium  and Magnesium, two essential minerals which help regulate heart beat and kidney output. Chinese Mineral Chi Tonic is one of the best synergistic formulas to help balance these minerals AND deal with stress, while increasing our vital energy.

Drugs accomplish nothing long-term to reducing stress, but there are many things you can incorporate into your life that will. Read how Dr. Bruce Lipton has shown how just one emotion such as love can physically change our genetic fate.

One simple exercise to begin today is the Gratitude Attitude – a recent Harvard study stated that saying 3 specific things per day for which you are grateful have been shown to decrease our metabolic age by 10 years in only 21 days! Other tips for emotional healing are included in Chapter 6 of Lorene Benoit’s book: The Paw Paw Program – The “Christopher Columbus” Approach to Cancer – The World IS Round and Cancer CAN Be Treated Naturally.

 

Ten Scientific Studies Prove that Genetically Modified Food Can Be Harmful To Human Health

The data “clearly underlines adverse impacts on kidneys and liver, two of our major detoxifying organs, as well as different levels of damages to heart, adrenal glands, spleen and haematopoietic system,” reported Gilles-Eric Séralini, a molecular biologist at the University of Caen.

Human health, of course, is of primary import to us, but ecological effects are also in play. Ninety-nine percent of GMO crops either tolerate or produce insecticides. This may be the reason we see bee colony collapse and massive butterfly deaths.  If GMOs are wiping out earth’s pollinators, they are far more disastrous than the threat they pose to humans and other mammals.

 

Vitamin C works on chicken pox, measles, polio – and without harmful side effects.

Dr. Frederick Klenner graduated from Duke University School of Medicine in 1936. In the “Clinical Guide to the Use of Vitamin C”, Dr. Lendon H. Smith outlines numerous cases on how Dr. Klenner quickly cured a variety of viral diseases by the use of intravenous vitamin C.

He reports of a ten month old baby with high fever, watery nose, dry cough, red eyes and rash characteristic of measles. Dr Klenner gave the baby 1,000 milligrams (mg) of vitamin C every four hours and the temperature dropped, the cough stopped and the rash disappeared.

Another eight-year-old child with measles developed encephalitis, became stuporous and responded only to pain. He quickly cured the child by both intravenous and oral vitamin C.

A 23 year old man with mumps developed swollen testicles, the size of tennis balls, along with overwhelming pain. After 1,000 mg of intravenous vitamin C the pain subsided. During the next 24 hours he was given 2,000 mg of intravenous C every two hours. His fever returned to normal in 36 hours and he was up and about in 60 hours.

Dr. Lendon Smith describes how Klenner discovered that intravenous C could also quickly dry up chicken pox lesions and subdue viral hepatitis.

But Dr. Klenner’s most important study involved the great polio epidemic of 1948-50. He successfully treated 60 polio victims using intravenous doses of vitamin C, up to 200,000 mg every 12 hours for four days. None developed paralysis. He soon learned that the sicker the patient the higher the dose required.

So we need to ask ourselves:

  • are we prepared to accept age old remedies that are now being proven by “science”, and even those that have stood the test of millennium but may never get funded by big pharma to prove they work?
  • how simple and inexpensive ate these remedies  compared to the cost and damaging side effects of pharmaceuticals and mass vaccination with toxic ingredients?
  • what can we do to keep our immune systems strong so that we do not offer ourselves as a host to germs and viruses that we are all exposed to on a daily basis?
  • why would we not WANT to take safe and affordable steps to ensure our optimum health?

Time to be pro-active about healthy living and successful aging! You may choose to start by taking this simple Health Assessment, then  contact the author with your score to help develop a plan of action to improve your health on a daily basis. It is your life and your health – embrace it!

Q & A Nerve Pain

Question:

Do you know of a treatment for nerve pain (feet and ankles)
EH from YT

 

Answer:

Nerve pain or neuralgia, can have many causes, and of course natural healing is not just about symptomatic relief, but getting to the root of the problem.

Are nerves being impinged or pressured in some way from a structural accident, posture or degeneration? For example a vertebral challenge, misplaced vertebra or bulging disk can put pressure on a nerve. If there is a physical or structural challenge, then this needs to be addressed for full resolution.

A restriction in circulation or injury can cause inflammation, and loss of nutrition reaching a nerve. This must be rectified to prevent degeneration of a nerve. As mentioned in The Paw Paw Program, Chapter 1 – “inflammation is the Root of All Evil”; it  affects all dis-ease conditions, including those that involve pain.

So without more detail, which would require a consultation,  it is  difficult to answer this more completely, but do seek out the cause.

From a pain reduction point of view, here are several formulations that we have used successfully over the past 25 years that can help with inflammation and pain in general, and nerve pain specifically. Herbs will also provide the nourishment necessary for  nerve  repair.

The following are some of the best anti-inflammatories from the herbal kingdom, some pain killers, and some topical applications which can all offer relief.

Please read these over and select two of the internal remedies, plus one topical. Try them conscientiously for at least one month. The beauty of this approach is that the herbs will have no negative side effects as most drugs do, and your body will benefit in some way from the added nutrition. You can see ingredients and benefits on these links, but links change, so please Contact us for up to date info and to get the best discount direct prices, plus free shipping. Personal service, no obligation.

Internal use taken orally to relieve inflammation and heal nerves:

Inflammation: Turmeric Curcumin  – concentrated standardized curcuminoid complex  (same name CA an US)

Nerve healing:

Stress Pack (CA)     Nervous System Pack (US)

Nerve health, tingling, vegetarians, digestion, memory:

Liquid Methyl B12 Plus (CA)  Liquid B12 Complete (US)

 

External use applied on skin to relieve inflammation and heal nerves:

Lobelia  

Tei Fu Massage Recovery Lotion: increases circulation;  helps relieve inflammation and pain; excellent for arthritis, sore muscles, sports injuries

Please contact us for current links to the professional products we have used since 1985, and to receive professional, personalized service with discounted prices.

 

Note: We adhere to the NSP policy and motto of  “Quality, Service and Integrity”. Ordering online (Amazon or EBay), is illegal, as an unknown seller cannot provide Service or Integrity, which we can. NSP has provided the professional Quality, exceeding pharmaceutical  standards,  since 1972.Ordering through our office will give you the best price and best service.

 

Paw Paw Program Upgrade

Update July, 2023

At Nature’s Sunshine 35th Canadian Health and Herbal Conference, Oct. 2011, I attended an excellent lecture from  Dr. Jay P. VandenHeuvel, PhD, ND on natural approaches to cancer.* This was an affirming lecture, as everything he mentioned is included in my book:  The Paw Paw Program – A “Christopher Columbus” Approach to Cancer – The World IS Round and Cancer CAN Be Treated Naturally. Based on recent research case studies that he and Dr. Gerry McLaughlin have conducted,  many people experience benefit by the addition of these singles and formula herbs to those presented in my book.

1. Taking Paw Paw (Asimina triloba) every six hours. This means 4 times per day, rather than 3, thus keeping a regular interval of 6 hours. In Dr. VandenHeuvel’s words, “Get the cancer by the throat and don’t let it go.”

Those who have read my book will understand this from my explanation of the exponential growth of abnormally reproducing cells. A little timer can help one accommodate this time frame. This may also mean that dosage can be increased to optimum chemo-therapeutic level. Remember this level is just below where you experience no nausea or other digestive or elimination challenge.

2. Addition of two herbs which I mention in my book: Pau D’Arco (p. 55 or 57)* and E-Tea (Essiac Tea p. 53, 202 or 55, 204)**.

These herbs have been traditionally used in cancer programs and are very effective. For simplicity, I suggest starting on the basic 4 program until you determine your optimum level of Paw Paw. Then based on Dr. VandenHeuvel’s successes, I  encourage these two herbs to be added to the basic 4 of The Paw Paw Program , if one is willing to add to their program.

For simplicity and effectiveness you can open 4-8 capsules Pau D’arco and add to 3 cups hot water; using a quart sealer or thermos if you want it to stay hot. Do the same with capsules of E-Tea. You can prepare each separately, or combine them. Some people prefer to have two different tasting teas to consume throughout the day. Taking them as a tea makes them more easily absorbed, as well helping you have adequate healthy liquid intake throughout the day. They can be used as your drink to take your other herbs.

NB:   As links tend to change over the years, please Contact us,  for personalized, expert assistance in obtaining any of herbs or supplements mentioned on this website. We have worked with one major quality professional herbal source since 1985 and can help you get the best for your health and your money. We offer all clients wholesale pricing. Do you want expertise and support or do you want a no-name, illegal Amazon seller? (Fine for household goods, but for your own health??)

Are you worth the best?

I prefer liquids to be taken at room temperature, and there is no problem with these teas sitting out for 24 hrs. If you do not like the taste of either of these, they can be taken as capsules, if you add at least 1 large cup of water to absorb and activate the herbs, with every dose of capsules.

As per explanations in my book about quality of herbs, the same holds true for both these herbs, as NSP species of Pau D’Arco contains the N-Factors (napthaquinone) and A-Factors (anthraquinones) required to be effective, and NSP E-Tea is the original Essiac formulation properly prepared and tested for potency.

In my consulting experience, many people are taking too many supplements. So I prioritize those that should be added, or suggest these to replace others that may be impotent, poor quality, or contradictory to their overall program. The top two additional choices  for me are Cat’s Claw Combination and Turmeric.

Cat’s Claw/Una de Gato is a traditional herb that has been the Peruvian cancer herb of choice for centuries. Cat’s Claw (CA) /  Una de Gato (US) combination has been combined with Echinacea and Astragalus. This formula cleanses and strengthens the immune, intestinal and structural systems and helps counteract the effects of chemotherapy and radiation by supporting the immune system. It is also an excellent lymphatic system support.

Turmeric Curcumin, is a potent blend of Turmeric (Curcuma longa)  which has been standardized to 95% curcuminoids and Black Pepper (Piper nigrum)for enhanced absorption.

As studies  and research show conclusive positive effects on reversing cancer, turmeric was mentioned  by almost every doctor in all 7  Asian countries in the 2019 Truth About Cancer. Besides anti-oxidant and anti-inflammatory effect, turmeric helps improve intestinal microbiome, and can help reduce pain.

Be sure to use one that contains enough curcuminoids, the active ingredient, to help!  We use a standardized concentrate. This means 2 vegi-capsules equal 1.4 pounds of whole turmeric root. For comparison, you might need 50 -200 capsules of regular turmeric capsules to have this potency, or try eating 1.4 pounds per day?!

If you do not have Lorene’s  book, which contains research, complete explanation of the program, references, and essential suggestions on diet, relaxation, recipes, and emotions, Contact Us now to order directly, PLUS receive wholesale pricing and our expertise.

 

*    Dr. Vandenhoeval’s “terminal” kidney CA diagnosis was  over 19 years, as of July, 2023. Good  thing he did not listen to or follow the voodoo hex of the medical prognosis. 

** page # depends on whether you have 1st, 2nd, or 3rd printing of Paw Paw book.                        3rd  Edition released Jan. 2020.