Paw Paw is an herb that is part of a natural program for cancer treatment. The correct species of this herb which has more than 30 years research, is Asimina triloba, which is native to the eastern U.S. Over fifty bio-active components of Paw Paw have been discovered in this particular species, specifically made from the tree twigs of a certain age. The major active compounds, which have been found effective in this cancer research, are called the annonaceous acetogenins. These have been described in a series of research papers as representing the most potent, major, bio-active structural types of acetogenins. These are only found in the standardized Paw Paw concentrate available from Nature’s Sunshine. The critical difference is in the quantity and quality of the active ingredient or acetogenins, found in this species.
The research from Purdue University by Dr. Jerry McLaughlin’s group, as well as Wayne State University, has shown that Paw Paw works as a chemotherapeutic agent, with no side effects. It has been shown to work via four specific mechanisms:
1) The acetogenins in Paw Paw modulate the production of ATP in the mitochondria of abnormal cells. All cells require energy to reproduce, but cancer cells are programmed to replicate at up to 17 times the rate of normal cell reproduction. Because acetogenins modulate the production of ATP, cancer and other abnormally growing cells do not thrive, while healthy, normally reproducing cells are unaffected. More technically, the acetogenins are potently cytotoxic and inhibit complex I in the electron transport system in mitochondria; the effect being depletion of ATP levels and induced apoptosis. They also inhibit the NADH oxidase found in the plasma membranes of tumour cells. This selective targeting affects the viability of abnormal cells will enhance the overall health of the body.
2) Paw Paw helps inhibit the growth of blood vessels that nourish cancer cells. This process is called anti-angiogenesis.
3) Paw Paw depletes the DNA and RNA building blocks necessary for new cell division. Although Paw Paw exhibits this action on abnormally growing cells, it has also been shown, in a recent clinical study with over 100 participants, that it supports the body’s normal cells. Studies with cell cultures of normal versus cancerous cells showed early on that the acetogenins are relatively less toxic to normal cells; indeed, certain acetogenins are often selectively cytotoxic toward one or only a few cancer cell lines. This means that whereas many cytotoxic drugs used cause cachexia, (weight loss), and energy loss, Paw Paw has shown opposite results.
4) The acetogenins are especially effective against multi drug resistant tumours (MDR), which can become resistant to the chemotherapy drugs. Paw Paw limits the ATP – dependant efflux pump (glycoproteins) function. Therefore Paw Paw can be toxic even to cancer cells that are drug resistant.
Paw Paw is a valuable tool in strengthening and supporting the immune system. Even if one chooses to use chemotherapy treatment, Paw Paw can actually enhance the effects of chemotherapy, as acetogenins are especially effective against multi-drug resistant (MDR) tumours, as per #4 above. (Please check out chemotherapy statistics and side effects before you make this decision.)
Previous clinical studies of the acetogenins in cancer patients have been thwarted due to their unavailability in pure form. Other related species such as graviola, guanabana, and Brazilian paw paw contain only the less potent monotetrahydrofuran acetogenins, and do not maximize acetogenin levels or standardize the product to assure consistent potency.
Paw Paw works in conjunction with enzymes, correct balance of essential fatty acids, minerals, immune enhancers, such as Silver Shield, Zambroza, Astragalus, and dietary, emotional and other lifestyle recommendations to ensure a holistic approach. For a more detailed scientific explanation, research, or case histories, contact Benoit & Associates Health Education.
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Feedback is always appreciated – that is how we all learn!
I have just come across an article that suggests that PawPaw is active against cancer. I have not swallowed the book of Knowledge but from the little research I have done I fond no corroborative evidence from clinical trials. In my now over 35 years of looking into natural remedies I would have thought I should if there is solid evidence.
However, there is 100% solid evidence that Curcumin, not curcumA, which is the spice turmeric, does prevent and cure all types of cancer. The controlled clinically proven success rate is substantial. Anything from skin cancer to TNBC is now being shown to be curable. http://www.curcuminresearch.org/cancer.html is a quick summary with thousands of clinical papers to back it up. Curcumin 99(TM) is use don hospitals where cancer is treated naturally with curcumin; so it is almost certainly better to go with what is clinically certain.
I am sorry and quite surprised you cannot find the Paw Paw research, as it is easily available. I list several many references in my book, The Paw Paw Program . But for your quick reference, here is a good link to some of Dr. McLaughlin’s extensive research: http://www.pawpawresearch.com/mclaughlin.html. To date, there are also at least 5 other books written on the subject and many other websites in addition to ours.
I also agree that curcumin complex, as found in Cure-Q-Min BP (US) and Cure-Q-Min (CA) is an excellent aid to health and has some benefits in cancer.
The concentrated tumeric compounds in this product have shown benefit for joint pain and other inflammatory conditions. It has been shown to exert a broad range of beneficial effects on various conditions, supports digestive and liver functions and is a blood tonic. For more on Cur-Q-Min and it’s benefits over medical pain relief, please read this article answering a question about Tylenol: http://www.naturalpathremedies.com/blog/qa/q-a-effects-of-t3-tylenol/
I have never seen the remarkable results with just this therapeutic as I have had with Paw Paw, Asimina triloba, taken in conjunction with the other essential elements of the program. I will look into more research, may add this to my Paw Paw program if warranted. Thank you for sharing!
To discuss how to order the best therapeutic quality curcumin complex OR the researched Paw Paw, please contact our office. First 10 minutes free.